Aspiration techniques for bronchoalveolar lavage in translational respiratory research: Paving the way to develop novel therapeutic moieties

Authors

  • Kamal Dua University of Technology and University of Newcastle
  • Shakti D. Shukla University of Newcastle
  • Philip M. Hansbro University of Newcastle

DOI:

https://doi.org/10.14440/jbm.2017.174

Keywords:

bronchoalveolar lavage, aspiration, respiratory

Abstract

Bronchoalveolar lavage (BAL) is a simple, yet informative tool in understanding the immunopathology of various lung diseases via quantifying various inflammatory cells, cytokines and growth factors. At present, this traditional method is often blended with several robust and sophisticated molecular and biological techniques sustaining the significance and longevity of this technique. Crucially, the existence of slightly distinct approaches and variables employed at different laboratories around the globe in performing BAL aspiration indeed demands an utmost need to optimize and develop an effective, cost-effective and a reproducible technique. This mini review will be of importance to the biological translational scientist, particularly respiratory researchers in understanding the fundamentals and approaches to apply and consider with BAL aspiration techniques. This will ensure generating a meaningful and clinically relevant data which in turn accelerate the development of new and effective therapeutic moieties for major respiratory conditions.

Author Biographies

Kamal Dua, University of Technology and University of Newcastle

DIscipline of Pharmacy (UTS) and School of Biomedical Sceinces and Pharmacy(UoN), Lecturer and Researcher

Shakti D. Shukla, University of Newcastle

School of Biomedical Sceinces and Pharmacy,àResearch Scientist (Immunology and Microbiology)

Philip M. Hansbro, University of Newcastle

School of Biomedical Sceinces and Pharmacy, Professor (Immunology and Microbiology)

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Published

2017-07-03

How to Cite

1.
Dua K, Shukla SD, Hansbro PM. Aspiration techniques for bronchoalveolar lavage in translational respiratory research: Paving the way to develop novel therapeutic moieties. J Biol Methods [Internet]. 2017Jul.3 [cited 2021Jul.28];4(3):e73. Available from: https://jbmethods.org/jbm/article/view/174

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